Emilien Demory

Postdoc (May 2013 – May 2015)

Chemical biography

Emilien completed his PhD at the Département de Chimie Moléculaire, University of Grenoble under the supervision of Pierre Yves Chavant and Véronique Blandin. Emilien’s doctoral research involved the synthesis of arylboronic esters and Pd-catalyzed direct arylation reactions.

In April 2013, Emilien joined our group on a Carl Trygger postdoctoral fellowship. His project involved a combination of catalytic C-H activation, (hetero)aryne and organoboronate chemistry. Emilien developed a new class of boryl (hetero)aryne precursors in which either the boronate or aryne reactivity can be activated selectively. The results were published in Angewandte Chemie (see right). In 2016 Emilien joined BioWorks in Uppsala and in 2017 he moved to work for Recipharm.

In early 2020, Emilien joined Thermo Fisher Scientific to become a project manager at their production site in Lyon, France.

Conferences

  • 3rd Nordic Meeting on Organometallic Chemistry, Lund, Sweden (March 11-12, 2015) – Poster

Publications

From postdoc work with us:

6. “Boryl (Hetero)aryne Precursors as Versatile Arylation Reagents: Synthesis through C-H Activation and Orthogonal Reactivity
Johanna Larsson, Emilien Demory, Karthik Devaraj, Carina Sollert, Lukasz T. Pilarski*
Synlett. 2016, DOI: 10.1055/s-0035-1561248

5. “Boryl (Hetero)aryne Precursors as Versatile Arylation Reagents: Synthesis via C-H Activation and Orthogonal Reactivity
Emilien Demory, Karthik Devaraj, Andreas Orthaber, Paul J. Gates, Lukasz T. Pilarski*
Angew. Chem. 2015127, 11931–11935
Angew. Chem. Int. Ed. 201554, 11765–11769

From PhD work in Grenoble:

4. “Efficient borylation of reactive aryl halides with MPBH (4,4,6-trimethyl-1,3,2-dioxaborinane)” N. PraveenGanesh, E. Demory, C. Gamon, V. Blandin P. Y. Chavant
Synlett 2010, 2403-2406

3. “Inexpensive, multigram-scale preparation of an enantiopure cyclic nitrone via resolution at the hydroxylamine stage
M. Thiverny, E. Demory, B. Baptiste, C. Philouze, P. Y. Chavant V. Blandin
Tetrahedron: Asym. 201122, 1266-1273

2. “Noncryogenic preparation of functionalized arylboronic esters through a magnesium-iodine exchange with in situ quench
E. Demory, V. Blandin, J. Einhorn P. Y. Chavant
Org. Process Res. Dev201177, 710-716

1. “Fast Pd- and Pd/Cu-catalyzed direct C-H arylation of cyclic nitrones. Application to the synthesis of enantiopure quaternary α-amino esters
E. Demory, D. Farran, B. Baptiste, P. Y. Chavant, V. Blandin
J. Org. Chem. 201277, 7901-7912

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Contact

Our group is part of the Organic Chemistry research program in the Department of Chemistry at Uppsala University’s Biomedical Centre (BMC).

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Department of Chemistry – BMC
Box 576
Uppsala University
75-123 Uppsala
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 lukasz dot pilarski at kemi dot uu dot se

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