Karthik Devaraj

Chemical biography

Karthik completed his B.Sc. in General Chemistry at St. Joseph’s College, Trichy, India. He then went on to do a M.Sc. degree at the National Institute of Technology in Trichy and wrote his thesis under the guidance of Dr. G. Venkatesa Prabhu.

He then went on to obtain his international Masters degree at the University of Rennes 1, France, where he worked in the group of Prof. Pierre Dixneuf and Prof. Christophe Darcel on Ru-catalyzed C-H functionalizations.

Karthik started his PhD in our group in August 2012. His doctoral research spanned new C-H functionalization reactions and the development of aryne-related methodology.

On 24th February 2017, Karthik defended his PhD thesis, entitled Ru-catalyzed C-H Functionalization of (Hetero)arenes, with Prof. Victor Snieckus of Queen’s University serving as the opponent. In doing so, Karthik became the first student to obtain his PhD from our research group. Congratulations, Karthik!

Karthik is now a postdoctoral researcher in the group of Xavier Bugaut at the Institut de Sciences Moléculaires de Marseille.

Conferences

• Organikerdagarna, Umeå, Sweden (14-16th June, 2016) – Talk
• 3rd International Symposium on C-H Activation, Montreal, Canada (30th May – 2nd June, 2016) – Poster
• 2nd International Symposium on C-H Activation in Rennes, France (June 30 – July 3 2014, 2014) – Poster
• 248th ACS National Meeting in San Francisco (August 10-14, 2014) – Poster

Publications

From PhD work in our group:

8. “Arynes and Their Precurors from Arylboronic Acids via Catalytic C-H Silylation”
Karthik Devaraj, Fredric L. J. Ingner, Carina Sollert, Paul J. Gates, Andreas Orthaber, Lukasz T. Pilarski*
J. Org. Chem. 2019, accepted

7. “Ru-Catalysed C-H Silylation of Gramines, Tryptamines and their Congeners”
Karthik Devaraj, Carina Sollert, Carmen Juds, Paul J. Gates, Lukasz T. Pilarski*
Chem. Commun. 2016, 52, 5868-587

6. “Selective Activation of Arylboronates or Aryne Reactivity as a Versatile Postfunctionalization Strategy”
Johanna Larsson, Emilien Demory, Karthik Devaraj, Carina Sollert, Lukasz T. Pilarski*
Synlett 2016, 27 (7), 969-976

5. “Boryl (Hetero)aryne Precursors as Versatile Arylation Reagents: Synthesis via C-H Activation and Orthogonal Reactivity”
Emilien Demory, Karthik Devaraj, Andreas Orthaber, Paul J. Gates, Lukasz T. Pilarski*
Angew. Chem. 2015, 127, 11931–11935
Angew. Chem. Int. Ed. 2015, 54, 11765–11769

4. “Ru-Catalysed C-H Arylation of Indoles and Pyrroles with Boronic Acids: Scope and Mechanistic Studies”
Carina Sollert, Karthik Devaraj, Andreas Orthaber, Paul. J. Gates, Lukasz T. Pilarski*
Chem. Eur. J. 2015, 21, 5380-5386

From Masters project in Rennes:

3. “Catalytic C-H bond arylation of aryl imines and oxazolines in water with ruthenium(II)-acetate catalyst”
B. Li, K. Devaraj, C. Darcel, P. H. Dixneuf
Tetrahedron 2012, 5179-5184

2. “Ruthenium(II) catalysed synthesis of unsaturated oxazolines via arene C-H bond alkenylation”
B. Li, K. Devaraj, C. Darcel, P. H. Dixneuf
Green Chem. 2012, 14, 2706-2709

From Masters work in Trichy:

1. “Study on the inhibition of mild steel corrosion 1,3-bis-(morpholin-4-yl-phenyl-methyl)-thiourea in hydrochloric acid medium”
K. Devaraj, D. Tamilvendan, G. V. Prabhu
J. Saudi. Chem. Soc. 2014, 18,  835-844